Real Madrid defeated Barcelona 2-1 to move top of the Spanish league log.
Toni Kroos increased the hosts’ lead with a deflected free-kick.
Lionel Messi has now gone eight Classico matches without scoring, his longest drought since making his Classico debut.
Messi and Valverde’s effort hit the bar before the end of the first half.
Oscar Mingueza reduced the deficit for Barcelona, but that was not enough to stop Real Madrid from going top of the log despite having the same point with Atletico Madrid.
The Los Blancos have a better head to head than their City rivals.
Casemiro was sent off in the 90th-minute following a rash challenge on Oscar Mingueza.