Sheffield United defeated Manchester United 2-1 at Old Trafford to boost their survival hopes.
Kean Bryan opened the scoring with a flicked header early in the first half to rattle Manchester United.
The hosts could not find their way back Into the game as Sheffield United ended the first half with a goal advantage.
Anthony Martial had a goal ruled out for offside as Manchester United toiled in search of the leveller.
Maguire restored parity with a glancing header just after the hour mark.
Oliver Burke scored the winning goal with 16 minutes to go as Manchester United failed to clear their lines as the effort deflected off Axel Tuanzebe to beat De Gea and subsequently have Sheffield United their first win over Manchester United since 1992.
Sheffield United remain rock bottom with ten points off safety, while Manchester United are in the second position on the log.
Manchester United Manager, Ole Gunnar Solskjaer was disappointed with the team’s performance.
“Disappointed, we couldn’t get to the heights of the last few months’ footballs we played. Very disappointing, we couldn’t find a solution to their very compact block and good defence”.
“Two wrong decisions, that’s how it is, it’s that kind of season, inconsistent and the referee missed those two”.
“That little spark, that edge, we didn’t have that extra creativity, imagination, the X factor we’ve had – it’s happened, we look at it, agree it is not good enough and go again.
We conceded a poor goal, lost the ball cheaply up the pitch, didn’t get back in and tackle, didn’t clear our lines and didn’t get out to the ball quick enough and we were punished.
Manchester United and Arsenal will battle it out in the Premier League on Saturday.